I'm confused how pyx would achieve this. In my experience unless uv/pyx is planning on pursuing being a new conda (and even then it's pretty incomplete), a single cohesive isn't possible because uv/pyx can't be the universal single source of truth. The value of Python has always been its ability to be integrated into a larger whole, and so the Python tooling must always defer to the tooling for the larger whole (and that space is composed of numerous competing tools and ecosystems). PyPI-provided non-pure wheels don't integrate well outside the ecosystem that's been built there, so I don't see how doubling down on it solves the underlying problem?