I'm sure it should help bring down the background levels of airborne pollutants, which should help as kind of a layered defence. But I expect it would be unlikely you could get it low enough to be in the same ballpark as a laminar hood, just because of the huge difference in air volume (the room is huge in comparison to the space the hood covers, so you need to filter way more, unless it was extremely well sealed in which case you'd just have to filter for long enough)